Acyanotic congenital heart disease includes heart problems that develop before or at birth but do not normally interfere with the amount of oxygen or blood that reaches the body's tissues. These problems include ventricular septal defect (VSD), atrial septal defect (ASD), and patent ductus arteriosus (PDA).

Acyanotic heart problems do not usually cause cyanosis—a bluish tint to the skin, lips, and nail beds due to reduced oxygen flow. If cyanosis develops in a person with an acyanotic heart problem, it is typically a sign that the heart can't pump enough blood and may need more oxygen.