Transsphenoidal adenomectomy is a type of surgery that may be used to remove a tumour (adenoma) of the pituitary gland, which lies at the bottom of the brain. Using a special microscope, the surgeon reaches the pituitary gland by threading tiny instruments through a person's nostril or into a small opening made in the bridge of the nose.

Once the tumour is removed, the remaining portion of the pituitary gland works normally in most cases.

Transsphenoidal adenomectomy is a very delicate procedure. People who need this surgery are often referred to medical centres that specialize in the technique.