Uses

Cloxacillin is used to treat a wide variety of bacterial infections. This medication is a type of penicillin antibiotic. It works by stopping the growth of bacteria.

How To Use

Depending on your specific product, this medication is given by injection into a vein or muscle as directed by your doctor, usually every 6 hours. The dosage is based on your medical condition and response to treatment. In children, the dosage is also based on weight.

If you are giving this medication to yourself at home, learn all preparation and usage instructions from your health care professional. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard medical supplies safely.

For the best effect, use this antibiotic at evenly spaced times. To help you remember, use this medication at the same time(s) every day.

Continue to use this medication for the full time prescribed, even if symptoms disappear after a few days. Stopping the medication too early may allow bacteria to continue to grow, which may result in a return of the infection.

Tell your doctor if your condition lasts or gets worse.

Side Effects

Upset stomach, nausea, vomiting, diarrhea, and gas may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including:

• nausea/vomiting that doesn't stop
• pain/redness/swelling at the injection site or of the arms/legs
• unusual tiredness
• joint/muscle pain or swelling
• easy bruising/bleeding
• signs of kidney problems (such as change in the amount of urine, pink urine)
• dark urine
• stomach/abdominal pain
• yellowing eyes/skin

This medication may rarely cause a severe intestinal condition due to a bacteria called C. difficile. This condition may occur during treatment or weeks to months after treatment has stopped. Tell your doctor right away if you develop:

• diarrhea that doesn't stop
• abdominal or stomach pain/cramping
• blood/mucus in your stool

If you have these symptoms, do not use anti-diarrhea or opioid products because they may make symptoms worse.

Use of this medication for prolonged or repeated periods may result in oral thrush or a new vaginal yeast infection (oral or vaginal fungal infection). Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge, or other new symptoms.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including:

• fever that doesn't go away
• new or worsening lymph node swelling
• rash
• itching/swelling (especially of the face/tongue/throat)
• severe dizziness
• trouble breathing

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before using cloxacillin, tell your doctor or pharmacist if you are allergic to it; or to other antibiotics including penicillin-type medications (such as amoxicillin, ampicillin, penicillin) or cephalosporins (such as cephalexin, cefuroxime); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of:

• kidney problems

This medication contains sodium. Consult your doctor if you eat a salt-restricted diet or if you have a condition that could be worsened by an increase in salt intake (such as congestive heart failure).

Cloxacillin may cause live bacterial vaccines (such as typhoid vaccine) to not work well. Tell your health care professional that you are using cloxacillin before having any immunizations/vaccinations.

Older adults may be more sensitive to the side effects of this drug.

Newborns may be more sensitive to the side effects of this drug.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

This drug passes into breast milk. Consult your doctor before breast-feeding.

Drug Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug include:

• methotrexate
• tetracyclines
• warfarin

Cloxacillin may cause false positive results with certain diabetic urine testing products (cupric sulfate-type). If you use these products, consult your doctor for more information. This drug may also affect the results of certain lab tests. Make sure laboratory personnel and all your doctors know you use this drug.

Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 9-1-1. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: mental/mood changes (such as confusion), seizures.

Notes

If you receive this drug for a long time, lab and/or medical tests (such as kidney/liver function, complete blood counts) should be done while you are using this medication. Keep all medical and lab appointments. Consult your doctor for more details.

Missed Dose

It is important to get each dose of this medication as scheduled. If you miss a dose, ask your doctor or pharmacist right away for a new dosing schedule. Do not double the dose to catch up.

Storage

Consult the product instructions and your pharmacist for storage details. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.