Pronunciation: koe-KANE HYE-droe-KLOR-ide
Important: How To Use This Information
This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
Cocaine is used by health care professionals to temporarily numb the lining of the mouth, nose, and throat (mucous membranes) before certain medical procedures (e.g., biopsy, stitches, wound cleaning). It is an anesthetic that works quickly to numb the area about 1-2 minutes after application. Cocaine also causes blood vessels to narrow, an effect that can decrease bleeding and swelling from the procedure.
How To Use
This medication is applied directly to the inside of the mouth, nose, or throat by a health care professional, usually right before your procedure. It may be poured, sprayed, or applied with a cotton swab directly to the area. When using this medication in the nose, your health care professional may soak absorbent material with the solution, then insert it into the nose. The dosage and application method depends on your condition and response to the drug. Do not give this medication by injection or use in the eye.
This medication numbs the mouth, nose, and throat. This effect will make swallowing difficult and increase your risk of choking or swallowing the wrong way. Do not eat or chew gum for 1 hour after this product is used or until your mouth/throat is no longer numb. It is especially important to make sure children do not eat or chew gum for at least 1 hour after their procedure. Be careful not to accidentally bite your tongue or mouth.
Dizziness, nausea, nervousness, unusual feelings of well-being, or restlessness may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if any of these unlikely but serious side effects occur:
- mental/mood changes (e.g., drowsiness, confusion, hallucinations, mood swings)
- numbness in application area several hours after procedure
- loss of smell or taste
- vision problems (e.g., blurred vision, sensitivity to light)
Tell your doctor right away if any of these rare but very serious side effects occur:
- slow/shallow/rapid breathing
- fast/slow/irregular/pounding heartbeat
- severe headache
- shaking (tremors)
Seek immediate medical attention if any of these rare but very serious side effects occur:
- chest pain
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including:
- itching/swelling (especially of the face/tongue/throat)
- severe dizziness
- trouble breathing
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Before your procedure, tell your doctor or pharmacist if you are allergic to cocaine; or to other ester-type anesthetics (e.g., benzocaine); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of:
- high blood pressure
- heart disease (such as chest pain, heart attack, irregular heartbeat)
- overactive thyroid (hyperthyroidism)
- infection/sores/injury in the area of the application site (such as the mouth, nose, throat)
This drug may make you dizzy. Alcohol or marijuana (cannabis) can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Avoid alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).
Caution is advised when using this drug in children because they may be more sensitive to the effects of the drug, especially restlessness/excitement.
Caution is advised when using this drug in the elderly because they may be more sensitive to the effects of the drug, especially irregular heartbeat and chest pain.
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
This drug may pass into breast milk and could have undesirable effects on a nursing infant. Therefore, breast-feeding is not recommended while using this drug. Consult your doctor before breast-feeding.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
Taking MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Avoid taking MAO inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine) during treatment with this medication. Most MAO inhibitors should also not be taken for two weeks before treatment with this medication. Ask your doctor when to start or stop taking this medication.
Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:
- stimulant-type drugs (including catecholamines such as norepinephrine or epinephrine, ephedrine, pseudoephedrine, amphetamines)
This medication may interfere with certain medical/laboratory tests (including brain scan for Parkinson's disease), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: vomiting, stomach/abdominal pain, severe headache, irregular breathing, seizures, fainting.
Store at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture. Do not freeze. Do not store in the bathroom. Keep all medicines away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.
Information last revised March 2019.
Copyright(c) 2019 First Databank, Inc.
Conditions of use: The information in this database is intended to supplement, not substitute for the expertise and judgment of healthcare professionals. The information in not intend to cover all possible uses, directions, precautions, drug interactions or adverse effects nor should it be construed in indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.